Understanding Dog Allergies in People and Dogs Alike

Written by: Pacagen Team
Reviewed by: David Zhang, PhD
David is an immunologist, bioengineer, and a scientific advisor at Pacagen.
Dog-related allergies are more complex than many people realize. While most people are familiar with the idea of being allergic to dogs, few know that dogs can suffer from allergies too. Understanding both sides of this equation — how dog allergens affect humans, and how dog allergies affect dogs themselves — is essential to creating a safe and healthy environment for everyone involved.
Dog allergens and human reactions
For people allergic to dogs, the primary trigger is not fur, as commonly believed, but proteins found in dog saliva, skin (epithelium), and urine. These proteins bind to dander — tiny, often invisible flakes of skin — which float in the air or settle onto surfaces like clothing, bedding, and clothing. The result? A range of allergy symptoms from mild sneezing and itchy eyes to severe asthma attacks in sensitive individuals.
One of the lesser-known but significant component of this reaction is a dog saliva allergy. According to the Asthma and Allergy Foundation of America (AAFA), when a dog licks your skin, it may cause localized reactions such as itching, redness, or hives — and once dry, these salivary proteins can become airborne and continue to contribute to the allergen load in your environment.
Some people develop allergies only after extended exposure, such as when bringing home a new puppy. You may not hear the phrase "allergic to puppy saliva" often, but it’s a very real immune response to allergens that can be just as potent in young dogs as in adults.
For those allergic to dogs, choosing the right breed is critical. While no dog is truly “hypoallergenic,” some breeds shed less or produce lower quantities of dander. Breeds with hair instead of fur, or those that require regular grooming, may release fewer allergens into the environment. These include certain smaller breeds —hence the growing interest in the idea of dogs for people with allergies, especially small breeds. Still, individuals with moderate to severe sensitivities should consult an allergist before adopting any pet.
Dog allergies in dogs: a growing concern
Just as humans can react to dog allergens, dogs can develop allergies too — especially to environmental triggers like pollen, dust mites, or mold. Dog allergies in dogs may also include food sensitivities and reactions to household chemicals. Seasonal allergies in dogs, particularly to pollen, are becoming increasingly recognized in veterinary medicine.
The signs of a dog pollen allergy may include:
- Excessive scratching or licking, especially of the paws and belly
- Recurrent ear infections
- Runny eyes or nose
- Inflamed skin or hot spots
- Sneezing and respiratory symptoms (less common)
Dogs that exhibit such symptoms in spring or fall may be reacting to tree, grass, or weed pollens — much like humans with hay fever.
Diagnosing allergies in dogs typically involves a physical exam, ruling out other issues (like fleas or mange), and sometimes intradermal skin testing similar to what is used for humans. It’s also important to differentiate environmental allergies from food-related reactions or contact dermatitis.

Managing dog allergies — in both species
Managing dog allergies depends on who’s affected — the human or the dog.
For humans, treatment focuses on reducing exposure. Strategies include:
- Frequent cleaning with HEPA-filter vacuums
- Use of air purifiers with high-efficiency filtration
- Restricting dogs from bedrooms or upholstered furniture
- Bathing the dog regularly to reduce dander
- Allergen immunotherapy (allergy shots or tablets) prescribed by an allergist
- Pacagen's dog allergen neutralizing spray may help reduce airborne and settled dog allergens.
For dogs, allergy treatment may include:
- Antihistamines or corticosteroids (under veterinary supervision)
- Medicated shampoos for soothing inflamed skin
- Allergen-specific immunotherapy (a growing veterinary practice)
- Dietary supplements to support skin health and immune response
- Avoiding high-pollen areas during peak seasons
According to the American Veterinary Medical Association, managing a dog’s allergy is most effective when it’s comprehensive — treating symptoms while also addressing root causes. It often requires patience as identifying allergens can take time.
Living together: solutions for people with dog allergies
Many people assume they can’t live with a dog due to allergies, but dogs for people with allergies are not out of reach. Choosing the right breed and implementing strong allergen-reduction habits can make a big difference.
Those with dog allergies should consult both a medical allergist and a knowledgeable vet before adoption. That’s because individual responses vary — one person might react severely to a dog that causes no issue for someone else, even within the same breed.
If owning a dog isn’t feasible, alternatives like spending limited time with therapy dogs or hypoallergenic robotic pets—may offer emotional support and companionship without triggering allergic reactions.
Conclusion
Dog-related allergies—whether affecting people or pets—are a nuanced topic that intersects biology, immunology, and lifestyle. By understanding the various types of dog allergens, recognizing the signs of dog allergies in dogs, and applying evidence-based strategies for treating dog allergies, it’s possible to navigate this complex relationship with clarity and compassion.
Both people and dogs deserve to breathe easy — and live comfortably — together.
References:
- Asthma and Allergy Foundation of America (AAFA) Pet Allergy
- American College of Allergy, Asthma & Immunology (ACAAI) Pet Allergies
- American Veterinary Medical Association (AVMA) allergic skin disease guidelines for dogs, cats
- Merck Veterinary Manual – Canine Atopic Dermatitis
- https://www.msdvetmanual.com/dog-owners/skin-disorders-of-dogs/allergies-in-dogs#Airborne-Allergies-(Atopy-or-Canine-Atopic-Dermatitis)_v3206998